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Kazuo Sugamura Selected Research

Cholangiocarcinoma

1/2021Discovery of a chemical compound that suppresses expression of BEX2, a dormant cancer stem cell-related protein.
12/2020BEX2 suppresses mitochondrial activity and is required for dormant cancer stem cell maintenance in intrahepatic cholangiocarcinoma.
6/2014Suppressive expression of CD274 increases tumorigenesis and cancer stem cell phenotypes in cholangiocarcinoma.

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Kazuo Sugamura Research Topics

Disease

21Neoplasms (Cancer)
08/2022 - 01/2002
6Infections
04/2009 - 03/2003
3Squamous Cell Carcinoma (Epidermoid Carcinoma)
08/2022 - 01/2019
3Cholangiocarcinoma
01/2021 - 06/2014
3Hypopharyngeal Neoplasms
10/2019 - 01/2013
3X-Linked Combined Immunodeficiency Diseases (X Linked Severe Combined Immunodeficiency)
01/2013 - 03/2006
3Inflammation (Inflammations)
04/2010 - 08/2003
3Hypoxia (Hypoxemia)
01/2009 - 03/2006
3Pulmonary Hypertension
01/2009 - 03/2006
2Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated)
03/2017 - 05/2016
2Carcinogenesis
02/2015 - 06/2007
2Atherosclerosis
12/2010 - 04/2005
2Necrosis
12/2010 - 10/2004
2Neoplasm Metastasis (Metastasis)
08/2008 - 06/2007
2Contact Dermatitis (Eczema, Contact)
08/2006 - 11/2002
2Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
10/2002 - 06/2002
1Esophageal Neoplasms (Esophageal Cancer)
08/2022
1Carcinoma (Carcinomatosis)
04/2020
1Melanoma (Melanoma, Malignant)
10/2019
1Squamous Cell Carcinoma of Head and Neck
01/2019
1Adenocarcinoma
01/2019
1Lymphoma (Lymphomas)
03/2017
1Stomach Neoplasms (Stomach Cancer)
01/2013
1Acute Monocytic Leukemia (Acute Monoblastic Leukemia)
01/2012
1Leukemia
01/2012
1Atherosclerotic Plaque (Atheroma)
12/2010
1Hepatocellular Carcinoma (Hepatoma)
10/2010
1Autoimmune Diseases (Autoimmune Disease)
09/2010
1Burkitt Lymphoma (Burkitt's Lymphoma)
09/2010
1Ovarian Neoplasms (Ovarian Cancer)
09/2009
1Pulmonary Arterial Hypertension
01/2009
1Neurodegenerative Diseases (Neurodegenerative Disease)
07/2008
1Ischemia
03/2007

Drug/Important Bio-Agent (IBA)

6Adapalene (Differin)FDA LinkGeneric
08/2022 - 01/2013
6Proteins (Proteins, Gene)FDA Link
08/2022 - 06/2006
5LigandsIBA
06/2014 - 11/2002
4OX40 LigandIBA
12/2010 - 04/2003
4CytokinesIBA
04/2010 - 04/2003
3Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)IBA
08/2022 - 01/2016
3Monoclonal AntibodiesIBA
08/2022 - 10/2003
2Glycoproteins (Glycoprotein)IBA
08/2022 - 04/2020
2Small Interfering RNA (siRNA)IBA
04/2020 - 06/2007
2AntibodiesIBA
02/2020 - 09/2010
2Biomarkers (Surrogate Marker)IBA
10/2019 - 01/2013
2Cytokine Receptors (Cytokine Receptor)IBA
01/2013 - 05/2006
2AllergensIBA
04/2010 - 04/2003
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
01/2009 - 03/2007
2ErythropoietinFDA Link
03/2007 - 03/2006
2HaptensIBA
08/2006 - 11/2002
2Prostaglandins DIBA
08/2006 - 08/2003
2Interleukin-2 Receptors (IL 2 Receptor)IBA
06/2002 - 02/2002
1ErbB Receptors (EGF Receptor)IBA
08/2022
1nanolucIBA
01/2021
1bis(4-methylumbelliferyl)pyrophosphateIBA
01/2021
1Adenosine Triphosphate (ATP)IBA
01/2021
1Carrier Proteins (Binding Protein)IBA
12/2020
1Mitochondrial Proteins (Mitochondrial Protein)IBA
12/2020
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
12/2020
1Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA
04/2020
1Nerve Growth Factor Receptors (Neurotrophin Receptors)IBA
10/2019
1Carbonic Anhydrases (Carbonic Anhydrase)IBA
03/2017
1Carbonic Anhydrase IXIBA
03/2017
1MK 2206IBA
05/2016
1MicroRNAs (MicroRNA)IBA
02/2015
1Long Noncoding RNAIBA
01/2013
1Matrix Metalloproteinases (MMPs)IBA
01/2013
1Apolipoproteins E (ApoE)IBA
12/2010
1Epithelial Cell Adhesion MoleculeIBA
10/2010
1Biological ProductsIBA
10/2010
1Rituximab (Mabthera)FDA Link
09/2010
1LuciferasesIBA
09/2009
1Proanthocyanidins (Procyanidins)IBA
04/2009
1Butanols (Butyl Alcohols)IBA
04/2009
1Pravastatin (Pravachol)FDA LinkGeneric
01/2009
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
01/2009
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2009
1alpha-galactosylceramideIBA
08/2008
1Endosomal Sorting Complexes Required for TransportIBA
07/2008
1beta CateninIBA
06/2007
1Phosphotransferases (Kinase)IBA
06/2007
1tyrosine receptor (receptor, tyrosine)IBA
06/2007
1Cadherins (E-Cadherin)IBA
06/2007
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2007
1Erythropoietin Receptors (Erythropoietin Receptor)IBA
03/2007
1Immunoglobulin E (IgE)IBA
08/2006
1Formyl Peptide Receptors (Formyl Peptide Receptor)IBA
08/2006
1prostaglandin D2 receptorIBA
08/2006
1Prostaglandin D2IBA
08/2006
1Immunoglobulin M (IgM)IBA
08/2006
1Immunoglobulin G (IgG)IBA
08/2006
1Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
03/2006
1Thymidine KinaseIBA
03/2006
1Ganciclovir (Cytovene)FDA LinkGeneric
03/2006
1Complementary DNA (cDNA)IBA
03/2006
1Interleukin-2 (IL2)IBA
09/2005

Therapy/Procedure

4Therapeutics
12/2020 - 10/2004
3Transplantation
05/2016 - 03/2007
2Heterologous Transplantation (Xenotransplantation)
05/2016 - 11/2002
2Immunotherapy
05/2004 - 02/2002
1Drug Therapy (Chemotherapy)
01/2021